ferndale pharmaceuticals ltd

There are no reviews for this business, be first to write a review! All patients should also be made aware of this possible adverse event and advised to immediately seek medical advice in case of any symptoms. There is no relevant use of Aethoxysklerol in the paediatric population in children or adolescents for the indication of sclerotherapy of varicose veins of the lower extremities. - When treating telangiectasias in patients with arterial occlusive disease (Fontaine stage II). - Anticoagulation is not a contraindication to sclerotherapy. When suggestions are available use up and down arrows to review and ENTER to select. by injection of 5,000 IU heparin or equivalents (if possible, into the affected artery; otherwise i.v. The puncture is carried out tangentially and the injection given slowly. The quality of microfoam depends on specific criteria: a) Concentration of lauromacrogol 400: In order to obtain a very fine-bubbled and stable microfoam, a concentration of 10-30 mg/ml must be used. Ferndale Pharmaceuticals Ltd Unit 740, Thorp Arch Estate, Wetherby, West Yorkshire, LS23 7FX, 8. It is not known whether lauromacrogol 400 is excreted in human milk. Depending on the size of the area to be treated, per puncture 0.1-0.2 ml Aethoxysklerol 2.5 mg/ml or 5 mg/ml are injected intravenously. 5% mg/ml) solution for injection, Aethoxysklerol 10mg/ml (1.0% mg/ml) solution for injection, Aethoxysklerol 30mg/ml (3.0% mg/ml) solution for injection. Generally, the dose of 2 mg lauromacrogol 400 per kg body weight per day should not be exceeded. Management of local toxicity after improper administration when treating varicose veins, 1. essentially 'potassium-free'. 2 and 3). Sclerotherapy of varicose veins should be used with caution in the following situations: - In patients with asymptomatic but known patent foramen ovale (PFO), it is recommended to use smaller volumes and avoid Valsalva manoeuvre in the minutes after injection. Lauromacrogol 400 caused haematuria in all species investigated. Additional proarrhythmic effects were seen when other local anaesthetics were given concomitantly. Depending on the diameter of the varicose veins to be treated, Aethoxysklerol 20 mg/ml or 30 mg/ml is used. Unit 124 St 2, Thorp Arch Estate, For the full list of excipients, see section 6.1. Get contact details, videos, photos, opening times and map directions. 89% of the administered dose was eliminated from the blood within the first 12 hours. Compression should not be applied immediately but 5 to 10 minutes after injection. Registered in England and Wales No. Directionshttps://www.yell.com/biz/ferndale-pharmaceutical-wetherby-5350690/#view=map. Continue, 2. Classification: Prescription only medicine. After sclerotherapy with microfoam the patient's leg is initially immobilised for 2-5 minutes. Solutions that contain particulate matter should not be used. Caution should be exercised when used in nursing mothers. This medicinal product does not require any special storage conditions. for the treatment of tributary varicose veins (collateral varices), up to 4-6 ml are injected per puncture. By treating acute inflammatory episodes of rosacea. Any residual amount must be discarded. In the meantime, thank you for your interest. Continue typing to refine. We are an equal opportunity employer and all qualified applicants will receive consideration for employment without regard to race, color, religion, sex, national origin, disability, protected veteran status, or any other protected status designated by federal, state, or local laws. Ferndale Pharma Group, Inc. For additional employment information, contact us at employment@ferndalelabs.com . Ferndale is committed to making sure you are satisfied with your purchase of DerMend, Heliocare, RectiCare, OC8, LMX 4, and LMX 5 products. Depending on the size of the varicose vein to be treated, per puncture 0.1-0.3 ml liquid Aethoxysklerol 10 mg/ml are injected intravenously. A thorough pre-procedure evaluation for valvular competency should be carried out as appropriate. The pharmacological action of lauromacrogol 400 is therefore considered to be locally restricted. When using microfoam, the leg can be placed horizontally or elevated approx. Smooth-moving disposable syringes are recommended for sclerotherapy as well as needles with different diameters, depending on the indication. 8). Pharmacotherapeutic group: sclerosing agents for local injection, ATC code: C05BB02. Preparation of sclerosing microfoam with Tessari technique: The syringes are firmly connected to a sterile three-way tap/valve (Fig. The vein is injected immediately (Fig. The risk increases with increasing Aethoxysklerol concentrations and volumes. Unit 740 Thorp Arch Estate, Wetherby, LS23 7FX. - Severe arterial occlusive disease (Fontaine stages III and IV), - High risk of thrombosis (e.g. Ferndale Pharmaceuticals Ltd was created by a management buy-out of a range of dermatology products from Ecolab (Adams Healthcare, Leeds) led by the company leadership team of Roger Bloxham and Roisin Wood and the majority shareholder Ferndale Pharma Group Inc, Michigan. After repeated administration of Aethoxysklerol, some animals of all species investigated showed histological alterations in the intestine, adrenal glands and liver, and rabbits additionally in the kidney. We work in partnership with the NHS and private healthcare providers to provide patient health and quality of life improvements. Depending on the size of the varicose vein to be treated, per puncture 0.1-0.3 ml Aethoxysklerol 10 mg/ml are injected intravenously. The divisions medicinal products are approved by the MHRA to be used by healthcare providers and patients to provide health and quality of life improvements for the following conditions: By providing surface anaesthesia of the skin. Click to access the summary of product characteristics and product information leaflet. Local adverse reactions (e.g. Compression treatment after injection of Aethoxysklerol. https://www.yell.com/biz/ferndale-pharmaceutical-wetherby-5350690/#view=map. Note: Syringes containing siliconized components produce a less stable foam and their use should be minimised. Use smaller volumes in these patients. 1). Lauromacrogol 400 is a local anaesthetic. A small family of speciality healthcare companies in the USA and Europe. Sclerosants must never be injected intra-arterially because this can cause severe necrosis which may necessitate amputation. Ferndale Pharmaceuticals Ltd was founded in 2003 and supplies its products to hospitals and pharmacies. migraine) after previous microfoam sclerotherapy, it is recommended that the patients should lie down for a longer time and avoid Vaslava manoeuvre in the minutes after injection. Adverse effects, including tissue necrosis, may occur following extravasation, therefore it is important to exercise extreme care in intravenous needle placement and use the minimal effective volume at each injection site. Preparation of sclerosing microfoam with DSS (Double Syringe System): The syringes are firmly connected to a sterile Luer Lock female-female adapter (Fig. Compression should be applied for a few days up to several weeks, depending on the extent and severity of the varicose veins. The most commonly reported side effects are temporary in most cases and include short-term injection site pain, injection site intravaricose blood clots and temporary skin discolouration after treatment. By continuing to browse the site you are agreeing to our policy on the use of cookies. In another study, the plasma concentrations of parent lauromacrogol 400 molecules were determined in 6 patients with varicose veins (diameter > 3 mm) after treatment with Aethoxysklerol 30 mg/ml. For information about any of the products, services or working at Ferndale Pharmaceuticals please contact us using the form below and we will be in touch with you shortly. In the long term, the affected veins are transformed into a fibrous cord. The frequencies seen below estimated from published data and spontaneous reports and are defined using the following convention: not known (cannot be estimated from the available data). Sclerotherapy of medium-sized varicose veins. © Yell Limited 2020. - Potassium, but less than 1 mmol (39 mg) potassium per ampoule, i.e. For information about any of the products, services or working at Ferndale Pharmaceuticals please contact us using the form below and we will be in touch with you shortly. A smooth, consistent foam is obtained. Wetherby, for the treatment of the saphenous veins, up to 4 ml are injected per puncture for the small saphenous veins and up to 6 ml for the great saphenous veins. The foam must be prepared just before use and administered by a physician appropriately trained in the correct generation and administration of foam. © Copyright 2020 - Ferndale Pharmaceuticals Ltd. Inward licensing & development of the product portfolio. known hereditary thrombophilia or patients with multiple risk factors such as use of hormonal contraceptives or hormone replacement therapy, obesity, smoking, and extended periods of immobility). Strict aseptic technique must be maintained while handling Aethoxysklerol. We work in partnership with the NHS and private healthcare providers to provide patient health and quality of life improvements. We work in partnership with professional skin clinics and skin savvy consumers to deliver skin and well-being enhancing results. The mean total clearance was 12.41 l/h and the distribution volume 17.9 l. In animal experiments, Aethoxysklerol has a relatively low acute toxicity. When using Aethoxysklerol 30 mg/ml microfoam, e.g. Once the injection site has been covered, a tight compression bandage or elastic stocking should be applied. necrosis), especially of the skin and of the underlying tissue (and, in rare cases, of the nerves), were observed when treating varicose veins in the leg after inadvertent injection into the surrounding tissue (paravenous injection). for the treatment of perforating or tributary varicose veins, up to 2 ml microfoam are injected per puncture. Start typing to retrieve search suggestions. Yell, Yellow Pages and other ™ are trademarks of Yell Limited. To bookmark a medicine you must sign up and log in. Both primary and secondary nonclinical pharmacodynamic studies show that the pharmacological profile of lauromacrogol 400 is characterized by its local effects on cell membranes and the associated, locally confined, damage to tissue. - Patients with bronchial asthma or a known strong predisposition to allergies. Sclerotherapy should not be undertaken if significant valvular incompetence is suspected following the evaluation. Adverse events should also be reported to Ferndale Pharmaceuticals Ltd on 01937 541122 The medicinal products are manufactured and released by pharmaceutical GMP certified facilities and we distribute them in accordance with pharmaceutical GDP operating under WDA Number: 20685

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